Archive

Archive for October, 2009

A brief view of the CRO industry

October 29th, 2009
Comments Off

Services provided by Clinical Research Organisations to the biotechnology, pharmaceutical and medical-device industries make it possible for clients to manage their product-development efforts more efficiently and at lower costs.

It is estimated that the global CRO market size is close to £35 billion and still growing, where it has been forecasted that revenue increases at an annual rate of fourteen to sixteen percent.

An investigation carried out by an independent analyst concluded that clinical trials conducted by CROs are competed on average 30 % quicker than those carried out in-house. This means a typical time saving of 4-5 months, equivalent to almost £300 million in increased revenue potential.

CROs are of an international industry. Leading Clinical Research Organisations will be acquainted with the associated rules, regulations and good clinical practices in place in many countries.

Approximately 100 thousand clinical professionals are employed by the Clinical Research Organisation industry on a global scale. They adhere to the highest ethical standards, complying with the Good Clinical Practices (GCP) and Good Laboratory Practice (GLP) put in place by regulatory authorities. CROs provide clients with an unmatched resource, therapeutic and regulatory proficiency, clinical and non-clinical drug development experience and up-to-the-minute technology.

CROs take a flexible approach and offer a number of services including, protocol writing and CRF design, clinical trial design, regulatory applications, data management, laboratory, pharmacy etc. This enables CROs to provide single service components or a complete full-service solution to their clients’ clinical trial needs.

The Drug Development Process

Introducing new drugs or medical devices to the market can take up to twenty years and can cost almost £2 billion to administer. A number of aspects contribute to the conduct of research, product development and clinical trials, which not only includes the clients’ staff but also physicians, academic research specialists as well as patients or volunteers. The flow of data between researchers and the sponsor must maintained by the information system managers and this is monitored by the relevant regulatory authorities. Before the commencement of a drug development program, experts in health economics and other fields will make an analysis of the market that the new drug or medical device will be entering in.

TIP: An indicator of a good CRO is the specialist equipment and facilities like a ecg core lab

This long-lasting, costly and complicated process is split into several stages. The first stage is known as pre-clinical research, lasting for 1-3 years, where new chemical entities or clinical devices are initially tested on animals. If these various tests prove to be effective and safe, the clinical testing in humans begins…

Related posts

Reviews

So You Want To Work From Home?

October 29th, 2009
Comments Off

An Introduction to Working from Home

Ask anyone to describe their ideal job and home working would come high on their wish list. Whether home working is an option provided by your employer or a decision you have taken yourself in starting your own business, the thought of just getting out of bed, walk over to a workstation and just start work is very appealing. No commuting to and from the office and working hours to suit yourself.

But is home or flexible working right for you as an individual, or good for your business as an employer? Well there are many advantages and disadvantages. Home or flexible working brings new responsibilities for both the employer and employee. Equally with advances in mobile technology it has never been easier to set up your own business to work from home.

An Increasing Trend

From a business point of view, allowing staff to work at home on either a full or part-time basis can bring a range of business benefits, from increased productivity, greater staff motivation to effective use of your premises. Advancements in mobile technology has contributed enormously to the increase in opportunities for working at home.

The spread of home working using the internet or telephone opens up a new range of possibilities with regards to the way a business works and structures itself. Computers, mobile phones, broadband and mobile broadband all play a role. For the individual, becoming self employed and working from home has also never been easier. If you have a laptop and mobile phone the opportunity is there, it’s just deciding what you want to do. So home working is becoming a way of life for many individuals and businesses, but what is home working?

Some employers will offer selected employees the opportunity to become a teleworker, whereby an employee can undertake their role from home utilising various types of technology, which is provided at the employees home by the employer. The employee will remain in touch with the business and other teleworkers. Some businesses, for example the utility companies who require gas, electric and meter readers, will class employees undertaking this type of work as teleworkers or outworkers.

Some individuals opt for the self-employed work life. The self-employed will operate their business from home, offering a product or service such as web development or business consultancy from home. In these types of roles, the individual can often plan their day to suit their own needs. I know one web developer who often works well into the early hours of the morning as this is when he feels most productive.

Others such as a painter and decorator, plumber or gardener, whilst providing their services away from the home, use home as the office for paperwork such as pricing future jobs and preparing invoices. I know of several painters and decorators who work Monday to Thursday, but use Friday’s to go out and price up future potential work. That is one thing to bear in mind when setting up as self employed, you need to allow time to find or prospect for future work.

Some types of work are more suitable for flexible working than others, the following list is not exhaustive, but will give some guidance:

  • Telesales and Marketing
  • Customer Services
  • Professional services & consultancy i.e. HR Administration & Accountancy
  • Certain types of administration work
  • Data input
  • Creative/Graphics
  • Writing, editing, translation and research.
  • I.T. Support & Programming

Many of the above have a common theme and that is that as long as you have access to a computer and a phone, you can undertake almost all of these tasks from home.

The shift towards flexible working does not mean employees only work from home. Splitting time between the workplace and home is the most productive solution, as you want employees to attend meetings, therefore keeping them informed and involved. Continued face to face interaction within the business remains a key requirement.

With the introduction of home working regulations, employers now have to seriously consider employee requests to work flexibly from home, especially if they have parental responsibility for children under 16 years old, disabled children or they are carers for other adults with disabilities.

Employers and individuals also need to consider what equipment will be required to ensure that an efficient business operation and working environment is set up.

Many accessories can complement office furniture to suit the home or office environment.

The Pros and Cons

So what are the advantages and disadvantages of an employer allowing employees to work from home or use their home as a base for at least part of the working week? It’s clear there are a number of benefits to the employer:

  • Staff Retention is increased
  • Wider pool of applicants to recruit from e.g. disabled people who prefer to work from home.
  • Productivity gains through having fewer interruptions and less commuting time.
  • Reduced stress and sickness increasing staff motivation.
  • Savings on office space and facilities.
  • Sales staff closer to clients, rather than being based at the office which could be miles away.
  • As with life if there are advantages then there are also disadvantages to home/flexible working:
  • Management of staff and monitoring performance
  • Possible deterioration of key skills and quality of work.
  • Capital costs - training and providing suitable equipment, this could include adaptations to meet Health & Safety standards or meet the needs of disabled workers.
  • Difficulties maintaining staff development and upgrading of skills.
  • Information security risks
  • Increased telecommunication and I.T. costs
  • Sense of isolation and communication problems amongst home workers.
  • Staff morale and difficulties in maintaining team spirit.
  • Home working may not be suitable for certain types of jobs.

One thing I particularly miss is the Monday morning office banter about what you did at the weekend of how your football team has fared compared to others. Often the camaraderie that is unique to an office where you get to know people well over many years is also lost where home working becomes an option.

Are You Suited o Home Working?

Having identified the types of work that is suitable for flexible working, the employer must satisfy themselves that employees are suited to this type of work. It’s likely they will need a number of skills in key areas to allow them to work away from base.

  • Time management and self discipline
  • Motivation
  • Communication
  • Technology

We must make it clear that home working is not suitable for everyone and care should be taken, because allowing one person to work from home will set a precedent that others will want to follow. Others will see an attraction to working at home particularly on a lovely summer’s day, rather than being stuck in an office. I must confess that as I write this article, I am sitting in our summer house at the bottom of the garden with the laptop on a glorious summer’s day in June.

An employer you must have a clear idea of how home/flexible working could fit in with the needs of the business. A set of house rules need to be established and maintained, i.e. priority is given to requests from parents of young or disabled children. My wife for example, plans her day around the hours of taking the children to school and collecting them later. She maintains that she is extremely focused on what she needs to achieve within those six hours in between. No distractions or idle chit-chat that will occur in an office environment.

In some cases the employer is legally obliged to seriously consider requests for home/flexible workers. Employee with parental responsibility for children aged 16 or under, or disabled children who are under 18 and receive disability living allowances can request a range of flexible working patterns from their employers, this includes the right to work from home. There are similar rights for employees who are carers of adults.

The introduction of flexible working can also lead to an overhaul to employment contract terms and conditions. In a majority of cases an employee’s place of work is listed in the written schedules of their employment contract. It’s important that when an employee starts to work from home it may be necessary to review and amend their employment contract.

The following is a list of contractual aspects an employer should consider when implementing a home/flexible work policy:

  • Stated hours of work
  • Identify core times when employees undertake to work and/or are contactable.
  • Extra duties or responsibilities that may need to be assigned in addition to those already agreed
  • Identify the terms regarding the supply and insurance of any equipment that may be required, these should clearly state ownership and use, especially that its not to be used for personal use.
  • Clearly identify what the employer will reimburse to cover additional expenses the employee may incur, its especially important to identify the calculation method when costs are shared i.e. utility bills and telecommunications
  • Procedures to be put in place if either the employee or employer wishes to terminate the home/flexible working arrangement.

Allowing flexible working the employer should remember that they still have health and safety responsibilities for people who work at or from home; and you are likely to have to provide and maintain equipment for employees to use, these include:

  • Workstation complete with suitable task chair
  • Filing cabinet, shelves or storage
  • PC/Laptop with office software, email and broadband internet connection
  • Dedicated business telephone line
  • Printer & fax machine
  • Stationery and Office Supplies

For added luxury, executive leather desk chairs are available for the home or office working environment.

IT equipment and software can be expensive so it’s important to ensure it meets your genuine business need and is compatible with your existing systems. Technology changes almost daily and with today’s advances the establishment of virtual teams where employees work together despite working at home can be set up easily and at reasonable expense. These teams could be two employees talking over the phone or you could use more hi-tech solutions like high speed internet, instant messaging, webinar and video conferencing. Many laptops now have web cam and this also offers the chance to see the person you are speaking with.

Providing all this kit and equipment it is important to ensure your business insurance cover is extended to cover home workers, as their home insurance is unlikely to cover this, however they should check with their insurer and extend their policy to cover working from home.It is also a good idea to find out who would be responsible for a claim should you have an accident at home, during working hours.

Workers who adopt home working should check with their local council and mortgage company the position regarding using their home as a work base, and whether they may have to pay business rates for the portion of their home they use as an office. Some self employed businesses will involve use of a vehicle which will need to be parked up at certain times of the day. For example painters and decorators and builders are likely to utilise a transit van or pick up truck in the work. You should therefore ensure that neighbours will not be offended by having the vehicle parked in the street or to block light out of their homes. If you are to park a vehicle at home, let the neighbours know, it may save a lot of hassle later.

The employer needs to ensure that employees take care of business equipment and information in their possession, it’s important to establish procedures to be followed if any item is damaged or lost, especially data and intellectual rights.

We all agree that home working offers a wide range of benefits to both the business and employees, but it needs to be carefully managed to be successful. Procedures should be put in place for managers to monitor and assess home workers, this is the most significant managerial challenge an employer will face. It can be helpful to measure their effectiveness in terms of output rather than the hours of work. Agree set goals and deadlines for particular tasks, and ensure these are being met, give feedback promptly and sensitively if things go wrong.

Ensuring home workers have access to training can prepare and help employees develop the necessary skills they need.For staff who work alone a sense of isolation is one of the main factors most likely to make home working fail, therefore it’s important to ensure procedures are put into place to make people feel part of the team, these should include:

  • Frequent two-way feedback sessions about work and work related issues
  • Regular visits to the workplace
  • Inclusion in social activities for home based workers.
  • Clear procedures to be followed and contact lists for when things go wrong.

When the employees job is entirely home-based from the start, make sure their initiation is undertaken at your premises, this helps the home worker focus and be productive if they have a chance to establish a clear idea of the people they will be working for.

I found that shopping online is where you will find the best buy office chair deals, often with furniture to match.

A Brief Health & Safety Obligations Check List for Home Workers

If you use your home as your main business workplace, you must carry out a health and safety risk assessment to identify any possible hazards to yourself, workers, visitors and other members of your household.

Possible hazards include:

  • Using work equipment at home, including electrical appliances
  • Your workstation set-up
  • Handling loads
  • Hazardous substances and materials
  • Psychological hazards, such as stress or loneliness
  • Fire
  • Slips, trips and falls
  • Excessive noise or vibration

Slips, trips and falls are one of the most common causes of injury in the work place. Even something we take for granted on a daily basis, such as walking up and down the stairs, should be regarded as a risk to safety. Evaluate whether a hazard is significant and if it is, whether you have taken enough precautions to make the risk as low as you reasonably can.

You need to consider:

  • Your home and those who live there - including vulnerable persons, e.g. children, the elderly, and new and expectant mothers
  • The work done in your home
  • The equipment in your home
  • Emergency procedures
  • First aid provision

Five steps to a health and safety risk assessment

  1. Identify any hazards.
  2. Decide who might be harmed and how.
  3. Assess the risks and remove them or, otherwise, reduce them as far as is reasonably possible.
  4. Record your findings.
  5. Check the risks regularly and take further steps if needed.

Conclusion

With advancements in mobile technology, working at home has become far easier to do. It can offer a very balanced way of life and the rewards can be great. In the current economic climate, many who have been unfortunate to suffer redundancy or reduced hours are considering setting up their own business to work from home. Having worked in the corporate world for over twenty years and just suffered redundancy, it is certainly something to consider.

But working from home needs to be considered carefully. Is it right for you? Is it right for your employer? What impact will it have on your homelife? Many advantages, but also many disadvantages and bear in mind the health and safety requirements and risks. Your health is important so choosing the correct office furniture to meet your needs is a must for any home worker to ensure you have the proper facilities for home working.

Another thing to consider, which is often overlooked, is that once you have got your work into your home, how do you get away from it?

If you are lucky enough to really love your work the temptation can be to do it all day long. Eventually this can lead to burn out and can also take away some of the pleasure of working, even if it is something you really love. Therefore it is important to have balance in your life, even more so when you work from home. Some suggestions to help to achieve this are to make sure that when you have lunch, for example, remove yourself from the work space and don’t eat at your desk, get some separation from the work when you are not doing it.

Remember that just because you work from home it doesn’t mean that work has to take over your life completely.

Related posts

Reviews

How To Care For Orchids

October 29th, 2009
Comments Off

Orchids are the most hardy and enduring plants in the word. They almost can grow steadily in any environment. Understand the environments carefully and how they affect the particular orchids that grow in them is very important.

So the first rule of thumb in orchid care is to know where your plants come from. Here is the short and simple guide. Epiphytes grow and flourish on tree trunks while hardy lithophytes make their home on rock and rock surfaces. While the myco-heterotrophs are those that lack chlorophyll and feed on nutrients from decaying plant matter. The last category and one in which a large number of today’s household orchid plants belong to are called terrestrial plants.

Phalaenopsis (Moth Orchid), Dendrobium, Cymbidium and the lovely Cattleya or the Corsage Orchid are the popular varieties for most household orchids. Remember not to take for granted that the common orchids can be easily taken care of.

One should consider that successful orchid care involves being aware that varieties still follow their geographic influences with some general rules.

Question, How To Care For Orchids

Orchid Care Tip 1: While orchids don’t need extra care and are not generally delicate, you should remember that if you’re living in a temperate country, only bring them out during the summer. In temperate climates, regular living room temperature is generally okay should you wish to display your prized specimens there.

Orchid Care Tip 2: Ask the nursery for orchids that can grow optimally in particular parts of your house; example, your porch, living room or window sill. Certain hybrids are bred for such special locations.

Orchid Care Tip 3: If you are a novice orchid grower, try a variety or hybrid that is easy like Phalaenopsis. The reason people love this variant because it can flower all year whereas the others only blossom once a year normally. In taking care of this variety, remember to always cut the stem after flowering to ensure that it blossoms again or grows a new stem segment.

Orchid Care Tip 4: It’s okay to give your orchids fertilizers. Make sure to follow certain conditions like the orchid’s flowering season. While general fertilizers are okay, try looking for special formulations specifically just for orchids.

Orchid Care Tip 5: If you are new to the orchid care, it is recommended to go online and participate in orchid related forums or websites, or join the horticultural societies. There is nothing more encouraging and fulfilling than sharing your new found passion with others who feel the same way of caring for orchids.

Cheapest Home Contents

Related posts

Reviews

5 essential tips and information on Cash Advance

October 29th, 2009
Comments Off

Cash Advance, Payday Loans, Payroll Loans, No Fax Loans, Cash Advance Payday Loans - these essentially mean one and the same thing - they all refer to seeking a loan in advance of the next payday or paycheck. This is broadly called the Payday Lending industry and is a multi-billion dollar booming industry. Statistics on this are all over the internet, so the focus of this article is not to dwell into known facts.

The focus of this article is to highlight and clarify a few essential tips and information related to the Payday Loan industry. This article is structured in an Q&A mode so you can get the bottom line information quickly and easily.

What exactly are Payday Loans?

Payday Loans are short-term loans, provided as cash, in exchange for receiving a check or promise of payment from the borrower’s, by way of automatic bank deposit or a check held for deposit in future. The amount of payback is usually the combination of the amount borrowerd plus finance charges for facilitating the payday loan transaction. If the borrower is able to authorize automatic bank withdrawals, on fixed dates (usually the upcoming pay days), the approval rate for the payday loan gets better.

How are Payday Loans different from a Bank Loan?

Payday Loans are cash loans, where the borrower receives immedite cash, just as in any other loan transaction. However, there are differences. Payday Loans are provided by independent third-party sources, and can often be obtained without detailed documentation or other processes one might have to go through in a typical bank loan transaction. This does come at a higher cost, though, as interest rates are typically higher than those in a Bank Loan transaction.

The amount that can be obtained in a Payday Loan is regulalated, and typically ranges anywhere from $100 to $1,500. The time of repayment varies, and could be from two weeks or more. On an annualized basis, the APR of the loan can be rather high, with numbers in the range of 400% or more. Since these transactions are typically repaid in a very short period of time, this type of loan favors those in immediate need of cash with the ability to pay back the loan amount within the next few pay periods.

How does one acquire a Payday Loan?

There are a variety of sources, both offline and online, from where one could acquire a payday loan. If one has a bank account in good standing, and has a reasonablly good ability to pay back the loan plus finance charge in time, one stands a good chance of qualifying for a payday loan.

What to look for in a Payday Loan provider?

Ultimately, of-course and needless to say, what to look for in payday lenders are their ability to fund your loan and make available the much needed cash. But what you ought to seek in a provider is much more than that. Some of the factors that you should consider include:

Speed of the approval process

Documentation requirement

Confidentiality of the transaction

Maximum amount that can be funded

Cost of the entire finance transaction including setup fees, early payment fees, penalties, interest rate, settlement fees etc.

Security of the transactional process

When to borrow?

As with any loan, borrow only when you absolutley must. Payday Loans can be a blessing in time of need, but it does come with a very high price. So, avail Payday Loans only when you must and when you know for certian that you have the ability to pay back in time. The cost of not paying back in time can be prohibitively expensive, including closing the doors for you to loan anymore in future. And even if you do meet the above criteria, avail the loan only if you must and have no other reasonable means of acquiring cash any other cheaper means.

View To A Bond

Related posts

Reviews